Yes: If the blood clot is in one of the major veins of the arm, it can lead to a fatal pulmonary embolus. The large veins of the arm are connected to the atrium. Fortunately arm DVT is less common than leg DVT but should not be taken lightly. It carries the same potential risks for embolism.
Answered 7/5/2016
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Very rare: Surprisingly enough, blood clots in the arms do not tend to be associated with pulmonary emboli as often as those clots in the legs. If your clot is in a superficial vein, it will never move, and so it poses no danger. If you have a deep clot (DVT) you need to be seen by a vascular surgeon to determine your risk of embolism and whether you need to be on a blood thinner.
Answered 10/4/2016
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