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A member asked:
Are ?congenital heart disease related to a faulty signal transduction pathway?
A doctor has provided 1 answer
Not likely.: Most congenital cardiac defects are due to multifactorial inheritance and environmental factors such as Folic Acid deficiency. I am not aware of specific studies linking them to a faulty signal transduction pathway, although such mechanisms frequently become the final common pathway of multiple etiological pathogenic factors.
Answered 7/4/2017
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