Considerable: Although Depakote and lithium are both prescribed and are effective for the treatment of bipolar d/o, they do differ.Depakote is actually an anticonvulsant medication prescribed for seizures, while lithium is not. The latter is basically a mineral and considered a mood stabilizing medication. Lithium is metabolized through the kidneys, while Depakote is through the liver.
Answered 5/15/2016
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