A 36-year-old member asked:
how is colon cancer inherited?
3 doctor answers
Dr. Edward Gold answered
43 years experience Internal Medicine
Genes: Most colon cancers are not inherited. However, there is a subset which is associated with inherited genetic abnormalities such as hereditary polyposis a this hereditary non polyposis gene (hnpp). There are also syndromes that make you susceptible to a variety of different cancers including colon cancer such as lynch syndrome.
Answered on Sep 28, 2016
Dr. Jeffrey Cohen answered
28 years experience Colon and Rectal Surgery
Genetics: There are inherited polyposis syndromes, and no polyposis syndromes. Most colon and rectal cancers diagnosed have no family history.
Answered on May 5, 2016
Dr. Douglas Brewer answered
33 years experience Colon and Rectal Surgery
Not simple answer: Cancer is when a cell won't die but can still divide and grow and hide from immune system. This is caused by many gene defects most of which happen after we are born. Sometimes we can inherit a defective cell growth gene from a parent Increasing our risk of cancer and it usually shows up earlier. This is why people with first degree family members with colorectal cancer get colonoscopy at 40.
Answered on Jan 16, 2016
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