Yes: A patient with a positive serology and rheumatoid arthritis can have severe disease. But also people who are seronegative can have severe damage. The highly positive seropositive patient can have more severe rheumatoid disease beyond the arthritis rheumatoid arthritis is a systemic disease of which arthritis is one manifestation. There can be systemic disease of eyes, lungs, heart to name some.
Answered 4/24/2013
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