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A 30-year-old member asked:

what is the difference between your cd3 and cd4 cells?

2 doctor answers5 doctors weighed in
Dr. Sue Ferranti
Internal Medicine 29 years experience
Types...: Cd3 and CD4 cells are different types of t-cells. T-cells are part of your immune system.
Dr. David Rosenthal
Allergy and Immunology 21 years experience
I think Dr. Ferranti meant to say that CD8 and CD4 cells are different types of T-cells. CD3 appears on "all" T-cells.
Jul 30, 2012
Dr. David Rosenthal
Allergy and Immunology 21 years experience
T-cells: All t-cells in the blood have the cd3 marker on their surface. In addition to having cd3 on them, most t-cells have either CD4 (if they are helper t-cells; th2-like) or cd8 (if they are cytotoxic t-cells; th1-like). There are many other types of t-cells (nkt, th17, treg, tr1, tfoll, th9) that make up a small number of the circulating t-cells. All of these t-cells have cd3 on them as well.

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A 28-year-old male asked:

What is the definition or description of: cd4?

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Dr. Alan Ali
Dr. Alan Alianswered
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CD4: Is a glyco protein found on surface of immune cells such as monocytes, macrophages & dendritic cells. It assists t-cell receptors in communicating with an antigen-presenting cell, hewnce facilitating entry of HIV virus into the cell. Measuring the CD4 count is used to determine prognosis in HIV treatment.

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Last updated Mar 20, 2018

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