HPA axis: Untreated anxiety, over time, leads to hyper-activation of the hpa (hypothalamic-pituitary-adrenal) axis, resulting in chronically elevated glucocorticoid (stress hormone) levels, which has been implicated in contributing to numerous disease processes, including heart disease, stroke, cancer, as well as weakening the immune system, increasing susceptibility to infectious diseases.
Answered 5/15/2019
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