A member asked:

Wegeners significance of + anca?

4 doctors weighed in across 2 answers
Dr. Thomas Namey answered

Specializes in Rheumatology

Most are ANCA+!: Wegener's granulomatosis is part of a larger group of vasculitic syndromes, all of which feature an autoimmune attack by an abnormal type of circulating antibody termed ancas (antineutrophil cytoplasmic antibodies) against small and medium-size blood vessels.Apart from wegener's, this category includes churg–strauss syndrome and microscopic polyangiitis.

Answered 10/18/2014

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Clinches diagnosis: And i'm glad it got made. Undiagnosed wegener's kills all its victims; today the large majority of folks are managed and most eventually remit. Dr. Wegener was sadly misled into joining the wrong political party, but still be grateful to his discovery that has saved so many lives.

Answered 9/14/2012

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