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A member asked:
Anyone have lupus or know any information on c4 complement?
5 doctors weighed in across 3 answers
C4 protein: Complement C4 is a blood test that measures the activity of a certain protein that is part of the complement system. The complement system is a group of proteins that move freely through your bloodstream. The proteins work with your immune system and play a role in the development of inflammation. This test is usually elevated in immune diseases or infections.
Answered 2/13/2015
5.7k views
Low levels = bad: Rheumatologists measure C4 and C3 levels in lupus because low levels are seen in active disease.
Answered 2/13/2015
5.7k views
C4 low?: C4 deficiency is commonly associated with sle. Therefore in this case it does not measure activity. To assess lupus activity, other than clinical findings, i always get a c2, c4, and a c3.
Answered 1/26/2013
5.7k views
Related Questions
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I have a lupus overlap. My C3/C4 have always been low, but this month C4 is at its lowest while C3 is a low normal. Why would it increase? ESR is up.
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