Have you ever heard of pseudoxanthoma elasticum? what is it?

Genetic: Pxe is a genetic condition that is transmitted in an autosomal recessive fashion, meaning when 2 unaffected partners possess a mutated gene; they can both pass the mutated gene down and cause pxe. Manifestations include early atherosclerosis (vessel disease) with leg pain on walking, a tendency towards bleeding, particularly in the eye. Skin manifestations are predominantly on folds.