Question about my heterochromia iridium - will it change with age?

Generally little.: Generally heterochromia iridium should change very little with age. The only change that could occur is any change that occurs in any tissue as a result of aging. In the case of the iris, the tissue may lose some of its melanin pigment as it ages. This may result in a slight noticeable change in the intensity of the difference in color of the two eyes.