A member asked:

What causes a baby to get tetralogy of fallot?

7 doctors weighed in across 2 answers

We don't know: In most cases tetralogy of fallot is thought to be "multifactorial", meaning that there are possibly genes, and also environmental factors which might increase a child's potential of having the defect.

Answered 9/23/2016



Multiple factors: It is still unclear what causes tof. There are both genetic and environmental factors that appear to increase the risk: poor maternal nutrition; alcohol consumption; maternal age > 40; maternal diabetes; maternal rubella; genetic disorders/syndromes (down syndrome or digeorge syndrome); parent or previous child with tof; maternal pku; maternal use of fluconazole, tegretol, or dilantin.

Answered 10/26/2013



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