How long can it take for local anesthesia injection to wear off?

Depends: It depends on what your doctor used. Most local anesthetic medications last about an hour. Some can last up to 24 hours, and there is a newer one that may not yet be available everywhere that reports that it can last up to 3 days.

Varies: Usually 1-2 hours depending on the anesthetic and if it has Epinephrine in it.

Varies: Some local anesthetics wear off within 30 minutes, while other are specifically designed to be active for up to 20 hours. It depends on the type and location of the drug. Talk to your anesthesiologist about medications that they will use.