Is there a difference between general anesthesia and twilight anesthesia?

Versed can: Be construed as conscious sedation, whereas general anesthesia implies laryngeal mask or endotracheal intubation to control air way. There are other twilight agents like propofol, which if not done under expert control may no be "twilight" but lights out...Forever.

Yes: Twilight anesthesia refers to 'conscious sedation', wherein a patient is sedated but arousable and breathing spontaneously. General anesthesia is a state of artificial coma or suspended animation from which the patient is unarousable and not breathing spontaneously. Prior to having any form of surgery requiring anesthesia it is important for you to get to know your anesthesia doctor.

Effects and depth: Twilight anesthesia is the application of sedatives to help the patient. One of the concerns is that there will be too much anesthesia given and the patient will not be able to breathe. This is for smaller operations. General anesthesia puts the entire body to sleep, and lets the anesthesiologist take over so that a surgeon is able to perform their operation.