A member asked:

How many (rough) hours would it take for an 88 yr man (with 15% kidney function) to wake up after given fentanyl 25 mcg (for 3 times)?

6 doctors weighed in across 3 answers

Maybe longer: I have seen the effects last upto three days in an older patient with kidney failure.

Answered 7/2/2012

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Variable: Fentanyl is not excreted by the kidneys, but older patients can be pretty sensitive. It may take an hour or more, but really depends on individual pharmakinetics.

Answered 8/5/2015

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Dr. Orrin Ailloni-Charas answered

Specializes in Anesthesiology

75 mcg of fentanyl: Is not a big dose for a normal sized adult (about 1mcg/kilo). I imagine that, unless it is combined with other meds, or the patient is otherwise debilitated, that this dose would sedate, but not knock out such a patient. It would take an hour or two to feel normal after this dose.

Answered 2/22/2014

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