A member asked:

About chemotherapy drugs, how can we reduce the diarrhea<side_effect> caused by them!?is it safe to use lupramide for these patients, oe not?

7 doctors weighed in across 3 answers
Dr. Michael Thompson answered

Specializes in Hematology and Oncology

Maybe: Some chemotherapy drugs are more prone to diarrhea then others (eg, irinotecan, docetaxel). Be careful with anti-diarrheal medications to make sure the diarrhea isn't infection, such as clostridium difficile colitis (c.Diff). Clinical trials looking at reducing diarrhea toxins -- eg irinotecan & casad- calcium aluminosilicate anti-diarrhea (basically a refined mud).

Answered 7/13/2012

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Dr. Liawaty Ho answered

Specializes in Hematology and Oncology

Chemo and diarrhea: Some chemo can cause diarrhea or other GI problems. You need to make sure you hydrate yourself well- fluids-fluids-fluids. Gatorade or pedialite would be good. If you think about antidiarrhea- you need to make sure that it is not infectious diarrhea- no bloody stool, no mucuous, no fever. Discuss with your oncologist in detail. If diarrhea continues for 2 days or so, you may need IV fluids +/- abx.

Answered 6/10/2014

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If doc says it is OK: As others have stated, it is essential to know why someone is having diarrhea before treating. Loperamide is commonly used for irinotecan-induced diarrhea, but it should never be used if there are concerns that an infection could be a cause. This can sometimes be difficult to figure out. Always talk with your oncologist.

Answered 12/23/2012

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