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A 39-year-old member asked:

How long do people with thrombocytopenia have to take anagralide?

2 doctor answers3 doctors weighed in
Dr. Joseph Woods
Pathology 29 years experience
You mean Anagrelide?: Apparently there is no such thing as anagralide, but Anagrelide is used to treat thrombocythemia or high platelet count rather than thrombocytopenia or low platelet count. It is a phosphodiesterase inhibitor, and inhibits pde-3 and phospholipase a2. Because of the liklihood of increased bone marrow fibrosis, and other side effects, it is not recommended as a first line therapy.
Dr. Liawaty Ho
Hematology and Oncology 24 years experience
ET: anagrelide is not indicated for thrombocytopenia. It is one of drugs used in essential thrombocythemia - i.e. having too much platelets. discuss with your hematologist in detail. anagrelide is not my first line therapy for ET. if you are on anagrelide- you may want to discuss with your MD about option of switching it when you grow older to other medication like hydroxyurea.

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Last updated Jun 25, 2014
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