Ischemia vs MI: Cholesterol plaque develops in the heart arteries. Progressive narrowing - usually greater than 70% - can lead to lack of blood flow to the heart muscle during exercise or rest and causes angina or ischemia. Myocardial infarction is due to the rupture of a plaque which causes a blood clot to form (thrombosis) in the artery blocking blood flow to that area of the heart muscle which then dies.
Answered 10/9/2018
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