A member asked:

Would someone with antiphospholipid syndrome have an increase of factor 8?

A doctor has provided 1 answer

Usually NOT: The mechanism of increased clotting in antiphospholipid syndrome (aps) is complex involving many levels of the clotting cascade. Although a paradoxical prolongation of the prothrombin or thromboplastin time is seen in the lab test (blood looks thinner), what happens inside the body could be the opposite - an increased risk of clotting that has nothing to do with levels of factor 8.

Answered 7/3/2012

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