A member asked:

Kidney transplant needed. confused about plasma exchange?

4 doctors weighed in across 2 answers
Dr. Cosme Manzarbeitia answered

Specializes in Surgery

ABO INCOMPATIBLE: Most plasma exchanges or plasmapheresis are done to be able to transplant people across the ABO group or in cases of extreme sensitization to other antigens. Results are variable, and depends on the desensitization protocol.

Answered 1/12/2015

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Removes antibodies: Plasma exchange or plasmapheresis is designed to remove antibodies (proteins) from the plasma fraction of the blood, which is then replaced with other plasma or albumin. It is done when the recipient has antibodies targeting the hla antigens in the donor. It may be done before or after the transplant; and is useful to prevent or treat rejections.

Answered 9/20/2012

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