What are the long-term risks of spit tobacco?

Oral cancer.: Oral, head, and neck cancers have alcohol and tobacco use, including smokeless as their biggest risk factors. Oral cancers can present as non-healing ulcers that can be painful. These patients usually present by age 50 but in susceptable people and those who use a lot of tobacco and alcohol, they can be seen at earlier ages.

There's a long list: Long-term use of smokeless tobacco increases risk of oral, esophageal, gastric, and pancreatic cancer. Smokeless tobacco products contain sugar, and can contribute to widespread tooth decay. They can also lead to heart disease. For more information, see the smokeless tobacco fact sheet maintained by the national cancer institute: http://www.Cancer.Gov/cancertopics/factsheet/tobacco/smokeless.