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A 36-year-old member asked:

how can i lessen side effects of cymbalta (duloxetine)?

2 doctor answers4 doctors weighed in
Dr. Susan Uhrich
Psychiatry 36 years experience
That depends on: What side effects you are having. In some cases, it may be better to treat the side effects and in other cases, it may be better to change the medications. Can you be more specific?
Dr. Alan Ali
Dr. Alan Ali answered
Psychiatry 32 years experience
Cymbalta (duloxetine): Taking Cymbalta (duloxetine) with food, or adjusting timing of daily dose such as 30mg. Twice daily instead of 60mg. Once daily, might help. Ofcourse, consult your doctor.

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A 29-year-old member asked:

Are generic versions of duloxetine as safe as the brand name drug?

3 doctor answers3 doctors weighed in
Dr. Kevin Considine
Family Medicine 30 years experience
Yes: Yes generic versions of duloxetine should be safe along with any other generics although i'm not sure that a generic of duloxetine is available yet?
CA
A 46-year-old member asked:

Does it make a difference whether I take my cymbalta (duloxetine) in the night or the morning?

4 doctor answers7 doctors weighed in
Dr. Barbara A Majeroni
Specializes in Family Medicine
Morning is better: Taken in the evening, Cymbalta (duloxetine) can cause insomnia, so it is better to take it in the morning.
CA
A 27-year-old member asked:

How quickly is it safe to increase my dose of cymbalta (duloxetine)?

3 doctor answers6 doctors weighed in
Dr. Leonard Raucher
Specializes in Family Medicine
1 weeks: You may safely increase Cymbalta (duloxetine) on a weekly basis.
CA
A 37-year-old member asked:

Will cymbalta (duloxetine) make me feel better right away?

2 doctor answers5 doctors weighed in
Dr. Alfredo Soto
Psychiatry 26 years experience
No: The effects of Cymbalta (duloxetine) will take from 1 week to 1 month depending on why you are using it. It can help symptoms of pain in 1-2 weeks, and depression in 1-4 weeks. It usually takes longer for Cymbalta (duloxetine) to help symptoms of anxiety.
A member asked:

What about cymbalta (duloxetine) discontinuation syndrome?

3 doctor answers6 doctors weighed in
Dr. Mary Ann Block
A Verified Doctor answered
A US doctor answered Learn more
Be very careful: Cymbalta, (duloxetine) like any ssri or snri, can create a physical dependency because of the effect they have on neurotransmitters. Everyone should be withdrawn from these drugs very carefully & cautiously. 3 weeks is the minimum one should take to reduce by each incriminate. Serious side effects, including suicide, have been reported when not properly.

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Last updated Aug 1, 2018

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