A member asked:

My husband passed away on an overdose of verapamil. please explain side effects and causes of death with a overdose of this nature. ?

6 doctors weighed in across 2 answers
Dr. H Robert Silverstein answered

Specializes in Cardiology

Slow the heart: There are 3 types of calcium channel blockers: first is norvasc/also called amlodipine. It opens the arteries fighting hbp, angina, and even raynaud's. 2nd is cardizem/diltiazem which is 1/2 way between Norvasc & verapamil (isoptin). Verapamil is the 3d and good for treating irregular heart beats, hbp, and angina as well as migraines. It likely slowed his heart &/or lowered the BP too far. Hrs.

Answered 3/8/2015

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Verapamil effects: Verapamil is designed to relax muscles both in the arteries and the heart. It also has a potent effect on the electrical system of the heart--slowing conduction. This latter problem would result in slowing of the heart rate, and in certain circumstances, severely so. The combination of digoxin & verapamil is well known to produce this kind of severe effect. There are many other drugs that interact.

Answered 10/17/2012

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