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A 41-year-old member asked:

Is it common to have high liver enzymes (alt/ast) with untreated hyperthyroid? i've read conflicting info. please help.

2 doctor answers5 doctors weighed in
Dr. Joseph Woods
Pathology 28 years experience
Not common.: This does not appear to have any consistent association with high alt/ast. Mainly this deals with low TSH (thyroid stimulating hormone) and high t4/t3 thyroid hormones. This condition does have an effect on the cells in your body, and causes weight loss and diarrhea, so the liver might be working harder than normal and so some enzymes like alt/ast might be high. See your dr. To be sure.
Dr. Ed Friedlander
Pathology 44 years experience
Both thyroid disease and undiagnosed liver disease are so common that many folks will have both by dumb luck. Get hemochromatosis, Wilson's, the various viral and immune hepatitis family diseases, and the metabolic syndrome ruled out, and no alcohol until you've done so. GOod luck.
Jun 14, 2012
Dr. Susan Wingo
Endocrinology 33 years experience
It's possible: Common? No. Possible? Yes. While most cases of hyperthyroidism do not cause elevated ast/alt, in more severe cases, this can be seen. Once the hyperthyroidism is treated, the ast/alt will be normal if the elevation was due to the hyperthyroidism. If not, they will stay high and need further workup. Good luck!

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Last updated Sep 28, 2018

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