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A 36-year-old member asked:

What's atherosclerosis from?

4 doctor answers7 doctors weighed in
Dr. Jeffrey Indes
Vascular Surgery 21 years experience
Multifactorial: Usually a combination of having a family history, diabetes, high blood pressure, obesity, high cholesterol, smoking. These are the main players.
Dr. Milton Alvis, jr
Preventive Medicine 42 years experience
White Blood Cells: Atherosclerosis is an accumulation of white blood cells, mostly macrophages (called monocytes, one of 5 white blood cell types), which have invaded into the walls of the blood vessel to remove low density lipoprotein (fat carrying protein) particles. The macrophages may die if overwhelmed with LDL & cannot export the ingested fat into high density lipoprotein particles. Also high glucose, bp, etc.
Dr. Milton Alvis, jr
Preventive Medicine 42 years experience
Provided original answer
Keep in mind that atherosclerosis, per se, does not narrow arteries. Instead, arteries enlarge at all the locations at which plaque develops (nearly always on inside curves of all bends). I figured this our in 1985 because the data did not match the theory about narrowing & this finding was first published in 1987: See: goo.gl/aRhOU2 Narrowings are the result of wall tears over plaques & clots.
Aug 30, 2014
Dr. William Cromwell
Clinical Lipidology 35 years experience
Multiple Factors: Atherosclerosis, also known as “hardening of the arteries”, occurs when areas of the artery wall thicken in response to either increased modifiable (high LDL particle levels, smoking or high blood pressure )and non-modifiable (genetics, age, gender) risk factors. Over time, areas of focal thickening may grow into a larger lesion called a “plaque" that can limit blood flow through the vessel.
Dr. J mark Rheudasil
39 years experience
Plaque: buildup of plaque and cholesterol deposits, etc. in the arteries--- "hardening of the arteries". Risk factors--- smoking, family history, high cholesterol, high blood pressure, age

Similar questions

A 43-year-old member asked:

What is the pathogenesis of atherosclerosis?

2 doctor answers2 doctors weighed in
Dr. Shadi Abu Halimah
Vascular Surgery 22 years experience
Multifactorial: Disease in the media( middle layer) of the artery with accumulation of fat, cholesterol into the wall causing inflammation which become chronic with special white blood cells called macrophages. Sometimes become calcified and sometimes can ulcerate or rupture into arterial lumen inducing emboli or clot/ thrombosis.
A 44-year-old member asked:

What are the characteristics of atherosclerosis?

2 doctor answers5 doctors weighed in
Dr. Charles Jost
Cardiology 37 years experience
Plaque build up: It is hardening of the arteries, caused by fat, cholesterol, and other substances building up in the arteries - this is called plaque - making the arteries stiffer. This plaque interferes with the normal function of the arteries and can cause problems and symptoms throughout the body. The plaque can block the arteries and/or it can break off and flow to smaller vessels and block them.
A 37-year-old member asked:

When does atherosclerosis develop?

2 doctor answers3 doctors weighed in
Dr. Latisha Smith
Wound care 39 years experience
Over a lifetime: Typically cholesterol plaques start to deposit in the arteries of the body as early as age 30. By the time someone is 50 years old and 20 years of plaque build up have occurred, the narrowed arteries can start to cause symptoms of low blood flow, such as chest pain with partially blocked coronary arteries. Atherosclerosis is a slow process and monitoring should be redone regularly.
A 38-year-old member asked:

Can atherosclerosis be a contraindication?

2 doctor answers4 doctors weighed in
Dr. Louis Grenzer
Cardiology 56 years experience
Depends: It depends on what you mean. A contraindication to what? Exercising, flying an airplane, playing a sport? And it also would depend on how bad the atherosclerosis is. If it has not narrowed arteries enough to cause symptoms, then it probably would not lead to any restrictions.
A 25-year-old member asked:

What is the epidemiology of atherosclerosis?

2 doctor answers2 doctors weighed in
Dr. Francis Uricchio
Cardiology 39 years experience
Wester lifestyle: Coronary artery disease is largely a disease of western civilization. As countries become more affluent, they exercise less, consume a diet with higher fat content, and gain weight. The prevalence of diabetes mellitus and coronary artery disease increases. Thus, coronary disease will become more frequent emerging countries such as india and china.

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Last updated Jun 2, 2017

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