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A 36-year-old member asked:

what's atherosclerosis from?

4 doctor answers7 doctors weighed in
Dr. Jeffrey Indes
Vascular Surgery 20 years experience
Multifactorial: Usually a combination of having a family history, diabetes, high blood pressure, obesity, high cholesterol, smoking. These are the main players.
Dr. Milton Alvis, jr
Preventive Medicine 41 years experience
White Blood Cells: Atherosclerosis is an accumulation of white blood cells, mostly macrophages (called monocytes, one of 5 white blood cell types), which have invaded into the walls of the blood vessel to remove low density lipoprotein (fat carrying protein) particles. The macrophages may die if overwhelmed with LDL & cannot export the ingested fat into high density lipoprotein particles. Also high glucose, bp, etc.
Dr. Milton Alvis, jr
Preventive Medicine 41 years experience
Provided original answer
Keep in mind that atherosclerosis, per se, does not narrow arteries. Instead, arteries enlarge at all the locations at which plaque develops (nearly always on inside curves of all bends). I figured this our in 1985 because the data did not match the theory about narrowing & this finding was first published in 1987: See: goo.gl/aRhOU2 Narrowings are the result of wall tears over plaques & clots.
Aug 30, 2014
Dr. William Cromwell
Clinical Lipidology 34 years experience
Multiple Factors: Atherosclerosis, also known as “hardening of the arteries”, occurs when areas of the artery wall thicken in response to either increased modifiable (high LDL particle levels, smoking or high blood pressure )and non-modifiable (genetics, age, gender) risk factors. Over time, areas of focal thickening may grow into a larger lesion called a “plaque" that can limit blood flow through the vessel.
Dr. J mark Rheudasil
Vascular Surgery 38 years experience
Plaque: buildup of plaque and cholesterol deposits, etc. in the arteries--- "hardening of the arteries". Risk factors--- smoking, family history, high cholesterol, high blood pressure, age

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CA
A 38-year-old member asked:

Is atherosclerosis hereditary?

5 doctor answers13 doctors weighed in
Dr. Charles Jost
Cardiology 36 years experience
It can be: Yes, atherosclerosis, cholesterol and many other factors can be hereditary - there is a genetic factor - but that is not the end of the story. Smoking, diabetes, overweight/obesity, diet, exercise, cholesterol control (i.e. The preceeding and medications) can influence the progress of atherosclerosis. 1st: know you numbers, 2nd: control the aforementioned factors and take your rx(s).
CA
A 35-year-old member asked:

Is atherosclerosis fatal?

3 doctor answers5 doctors weighed in
Dr. Charles Jost
Cardiology 36 years experience
Can be: Artherosclerosis is a progressive disease. As plaque builds up throughout the cardiovascular system and interferes with the normal functioning of the body, it can be fatal. This explains why heart disease is one of the main causes of death.
A 50-year-old member asked:

What causes atherosclerosis?

3 doctor answers6 doctors weighed in
Dr. Jerry Routh
Internal Medicine 46 years experience
Cholesterol Plaque: Atherosclerosis is the build up of cholesterol and calcium plaque in the arteries of the body. It is due to injury of the artery wall and inflammation which attracts blood cells which promote cholesterol deposition in the arteries. Known conditions which are associated with atherosclerosis include family history, smoking, hypertension, diabetes, elevated cholesterol/ldl or low hdl, and age.
CA
A 23-year-old member asked:

What does atherosclerosis mean?

2 doctor answers6 doctors weighed in
Dr. Charles Jost
Cardiology 36 years experience
Plaque build up: It is hardening of the arteries, caused by fat, cholesterol, and other substances building up in the arteries - this is called plaque - making the arteries stiffer. This plaque interferes with the normal function of the arteries and can cause problems and symptoms throughout the body. The plaque can block the arteries and/or it can break off and flow to smaller vessels and block them.
A 37-year-old member asked:

When does atherosclerosis develop?

2 doctor answers3 doctors weighed in
Dr. Latisha Smith
Wound care 38 years experience
Over a lifetime: Typically cholesterol plaques start to deposit in the arteries of the body as early as age 30. By the time someone is 50 years old and 20 years of plaque build up have occurred, the narrowed arteries can start to cause symptoms of low blood flow, such as chest pain with partially blocked coronary arteries. Atherosclerosis is a slow process and monitoring should be redone regularly.

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