What causes scleroderma in people?

Unknown: The precise cause is unknown but there is a genetic predisposition in certain individuals. Viruses, certain drugs, and environmental factors have been considered as potential triggers for the onset of scleroderma in genetically susceptible persons.

I hate: As a surgeon to get involved but i lost my wife in just two years... It is an autoimmune disease of unknown origin. When just suspected a sedimentation rate, ANA levels, anti scl-70 and anti-centromere antibodies should be stat done. A good resource is this web site: http://www.Synnovation.Com/sclerodermafaq.Html i would seek help from a university based rheumatology department...