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A 48-year-old member asked:

what is interstitial cystitis caused by?

2 doctor answers7 doctors weighed in
Dr. Mitchell Schuster
Urogynecology 32 years experience
Breakdown in GAG: There is a breakdown in the gag layer of the bladder. Gag stands for glucoseaminoglycan and it is a microscopic layer that is supposed to help with protection of the mucous layer of the bladder. There is a lot of research going into this area and there is a significant connection between interstitial cystitis and endometriosis. Right now we are managing the symptoms as best we can. No cure yet!
Dr. Stephen Rodrigues
A Verified Doctor commented
A US doctor answered Learn more
This is a new look at an old idea. Janet G. Travell, MD a pain pioneer concluded that chronic tissue pain was caused by numerous trigger points in muscle fibers causing the muscles to contract compressing nerves, vessels and alter the flow of lymphatics. The pyramidalis and pelvic floor muscles are the cause. So this is a mechanical cause and requires a manual treatment. Massage and Acupuncture! See files.
Nov 22, 2012
Dr. Robert Harris
Urogynecology 31 years experience
Unknown: Although IC seems to be more common in women with other ayto0immue processes, there is no known "cause" for IC. Interstital Cystitis is more of a compilation of symptoms rather that a true "condition". Therefore, treating the symptoms, e.g. urinary frequency and urgency, pain in the bladder area, painful intercourse, pelvic pain, etc., is the best approach to improving outcomes.

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A member asked:

Can I take medication for utis while breastfeeding?

3 doctor answers6 doctors weighed in
Dr. Scott Katz
Pediatrics 26 years experience
Yes: Most antibiotics are safe while breastfeeding, but some are not. Make sure the prescribing physician knows you are breastfeeding. If you have a concern, please call your pediatrician.
A member asked:

Will the doctor do tests after my baby has a uti?

13 doctor answers25 doctors weighed in
Dr. Lisa Roberts
Pediatrics 23 years experience
Yes: Typically in a young infant who has the first UTI associated with fever, tests are done make sure there is no reason why it may happen again. A renal ultrasound is done to check the kidneys & bladder to make sure there is no anatomic deformity. A VCUG study is a test that involves inserting a tiny catheter into the bladder to make sure there is no reflux of urine that goes back towards the kidney.
A 21-year-old member asked:

What is the cause of interstitial cystitis?

2 doctor answers3 doctors weighed in
Dr. Alfredo Nieves
Gynecology 40 years experience
IC cause: There is a lack of a protective coat in the bladder that exposes the nerve fibers in the bladder to the urinary irritants.It seems that there is a deficit in an antiresorptive substance that maintains the integrity of this coat in the bladder tissue.
A 45-year-old member asked:

Is it normal to have a UTI without a burning sensation or foul smell?

1 doctor answer1 doctor weighed in
Dr. George Klauber
Specializes in Pediatric Urology
Yes: It is quite possible to have utis without any symptoms. Not infrequently pseudomonas and proteus utis can be symptom free.
Nigeria
A 25-year-old female asked:

How can interstitial cystitis be managed? Can it be the cause for reoccurring pyelonephritis? Any drugs for interstitial cystitis that can help?

1 doctor answer1 doctor weighed in
Dr. Stephen Chinn
Urology 38 years experience
Elm iron: Ic is a chronic inflammation in the "wall" (interstitium) of the bladder resulting in pain, frequency and blood in the urine. Reportedly more common in women, it is probably well under diagnosed in men. Best managed with dietary/lifestyle (hydration), there is only 1 medication approved by the fda - elmiron, (pentosan) to "fill the cracks" in the bladder lining. Intravesical (in the bladder) txs available.

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