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A 48-year-old member asked:

What is interstitial cystitis caused by?

2 doctor answers7 doctors weighed in
Dr. Mitchell Schuster
Urogynecology 33 years experience
Breakdown in GAG: There is a breakdown in the gag layer of the bladder. Gag stands for glucoseaminoglycan and it is a microscopic layer that is supposed to help with protection of the mucous layer of the bladder. There is a lot of research going into this area and there is a significant connection between interstitial cystitis and endometriosis. Right now we are managing the symptoms as best we can. No cure yet!
Dr. Stephen Rodrigues
A Verified Doctor commented
A US doctor answered Learn more
This is a new look at an old idea. Janet G. Travell, MD a pain pioneer concluded that chronic tissue pain was caused by numerous trigger points in muscle fibers causing the muscles to contract compressing nerves, vessels and alter the flow of lymphatics. The pyramidalis and pelvic floor muscles are the cause. So this is a mechanical cause and requires a manual treatment. Massage and Acupuncture! See files.
Nov 22, 2012
Dr. Robert Harris
Urogynecology 32 years experience
Unknown: Although IC seems to be more common in women with other ayto0immue processes, there is no known "cause" for IC. Interstital Cystitis is more of a compilation of symptoms rather that a true "condition". Therefore, treating the symptoms, e.g. urinary frequency and urgency, pain in the bladder area, painful intercourse, pelvic pain, etc., is the best approach to improving outcomes.

Similar questions

A 21-year-old member asked:

What is the cause of interstitial cystitis?

2 doctor answers3 doctors weighed in
Dr. Alfredo Nieves
Gynecology 41 years experience
IC cause: There is a lack of a protective coat in the bladder that exposes the nerve fibers in the bladder to the urinary irritants.It seems that there is a deficit in an antiresorptive substance that maintains the integrity of this coat in the bladder tissue.
A 18-year-old member asked:

What are the causes of cystitis?

4 doctor answers10 doctors weighed in
Dr. Danny Proffitt
Family Medicine 44 years experience
Infection/irritation: Cystitis is an inflammation of the bladder. It is usually due to an acute bacterial infection. There are other causes due to inflammatory responses not able to be discussed here. Force fluids, try otc bladder anesthetics (azo-standard) and watch. If you don't resolve quickly, get seen and treated. Fever, chills, nausea, vomiting and abdominal pain are warning signs for immediate attention.
A 36-year-old member asked:

If you have interstitial cystitis can it cause you to have infections?

2 doctor answers4 doctors weighed in
Dr. Stephen Chinn
Urology 39 years experience
IC causing UTI: Usually no; although the symptoms of an acute "flare" of ic can mimic those of a uti, and some of the treatments for utis (eg nitrofurantoin/macrobid/......) have been implicated in causing/aggrevating ic in pts with known disease.
A 48-year-old member asked:

Interstitial cystitis -- what is it?

7 doctor answers14 doctors weighed in
Dr. Lester Thompson
Pathology 34 years experience
Bladder inflammation: The bladder has several layers, starting from the lining, through the muscle to the serosa (outer lining). The "interstitium" is between the muscle bundles. An inflammation of this area, results in "cystitis". It does not mean an infections, but it often is.
A 34-year-old member asked:

Can interstitial cystitis cause bloody discharge?

3 doctor answers6 doctors weighed in
Dr. David Miller
Dr. David Milleranswered
Family Medicine 11 years experience
Bloody urine: Interstitial cystitis is a chronic inflammation of the lining of the bladder. The cause is not well understood (although it's most likely not an infection) and it can be difficult to treat. About a third of patients will have blood in their urine. This is not typically referred to as a "bloody discharge, " however.

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Last updated Jun 20, 2017
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