Hormonal: Adrenal gland has two functionally different parts and tumors of these have different symptoms. Tumors of the medulla, pheochromocytoma, cause high blood pressure and related symptoms. Cancer of the cortex, if functional, cause increased amount of corticosteroids resulting in fragile skin, fluid retention, hypertension etc. Mets produce symptoms based on organ affected by mets.
Answered 6/11/2012
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