A member asked:

How does alcohol affect zosyn (piperacillin and tazobactam)?

9 doctors weighed in across 3 answers
Dr. Gutti Rao answered

Specializes in Hospital-based practice

Decrease effective: Alcohol with zosyn (piperacillin and tazobactam), (piperacillin and tazobactam) decreases the effectiveness of the antibiotic and increase its side effects. Most often zosyn (piperacillin and tazobactam) is given in a hospital setting, and the likelyhood of consuming alcohol is almost nil in the hospital.

Answered 12/21/2017

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Dr. Michael Ein answered

Specializes in Infectious Disease

No: No problem taking penicillin class antibiotics with alcohol but keep it to a minimum if at all. If you have a significant infection it would be best to abstain until the infection has resolved.

Answered 10/17/2018

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Dr. Susan Uhrich answered

Specializes in Psychiatry

It will: Likely reduce the effectiveness of the zosyn (piperacillin and tazobactam).

Answered 12/21/2017

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