U.S. doctors online nowAsk doctors free
Rockaway, NJ
A 29-year-old female asked:

Missed dose of 100mg zoloft (sertraline) on monday. took regular dose on tuesday. what will happen if i miss wednesday's dose?

1 doctor answer1 doctor weighed in
Dr. Marc Zimmermann
Psychiatry 23 years experience
Less Effective: Missing doses decreases the amount of the medication in your system and will lessen the effectiveness of the medication. The half-life of Zoloft (sertraline) is 26 hours. When you do not take it for a day, the medication in your system is roughly half of what your doctor feels you need.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Jun 20, 2021


Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.