A member asked:

Hook effect in pregnancy? can it cause false negative hpt 8 weeks after lmp.

A doctor has provided 1 answer

Possible ..: Its possible but not common. After 6 weeks there is a higher concentration of HCG beta core fragment and this can cause the Hook Effect. In some tests this has caused false negatives. Some of the newer tests such as the "First Response Early Result" are supposed to be modified to prevent this uncommon problem. Best wishes!

Answered 2/3/2015

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