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A member asked:
Which enzyme has impaired activity in someone with a vitamin b1 deficiency?
A doctor has provided 1 answer
Pyruvate: The vitamin B1 dependent enzyme is the decarboxylase, one of 3 enzymes that make up the pyruvic dehydrogenase complex. Essential in the oxidation of glucose, the major fuel of the brain. No cellular energy without B1! Unusual fatigue is a common symptom.
Answered 4/8/2021
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