A member asked:

Metaplasia may carry some risks, but does it necessarily prevent the esophagus/stomach from functioning properly--prevent either from doing its job?

2 doctors weighed in across 2 answers

It does not: Apart from some forms being an occasional breeding ground for malignancy, it's harmless.

Answered 2/11/2015

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No: Intestinal/gastric metaplasia of distal esophagus means replacement of the squamous epithelium with glandular (Barrett's esophagus) and is often associated with gastro-esophageal reflux disease (regurgitation of gastric acid into the esophagus which causes "acid burn" (heartburn) and inflammation. If the latter is severe, it may interfere with the entire digestive activity

Answered 1/28/2015

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