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A female asked:

what is the difference between multiple myeloma and waldenstrom macroglobulinemia?

1 doctor answer1 doctor weighed in
Dr. Ed Friedlander
Pathology 44 years experience
Paraprotein: Waldenstrom's looks like a low-grade lymphoma rather unusual plasma cells, and produces IgM pentamer molecules instead of IgG or IgA monomers or free light chains. It tends to occupy lymph nodes rather than marrow. Hyperviscosity of the blood is likely to be the most troublesome feature.

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Last updated Feb 20, 2020

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