Can i use methylprednisolone & motrin together?

You can: But beware, this is a chance the combination could really irritate your stomach. Make sure you take the motrin with food. And let your doctor know if you are having stomach pain or nausea.

Avoid: Methylprednisolone and Motrin (ibuprofen) are anti inflammatory medications. Taking the two together can increase risk of side effects including gastritis. If you need a pain medication when on methylprednisolone then take acetaminophen. Do not ever take more than the recommended dose of any medication.

Usually ok: However, per Drugs.com drug interaction checker - be mindful for "unusual bleeding, severe abdominal pain, dizziness, lightheadedness, and the appearance of black, tarry stools."