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A 43-year-old member asked:

What neurotransmitters are released by opioid usage?

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Dr. Paul Grin
Dr. Paul Grinanswered
Pain Management 38 years experience
Endorphins: Because C-fibers release several excitatory neurotransmitters (e.g., substance P. CGRP), activation of opioid receptors will reduce the release of these transmitters from the presynaptic terminals of afferent sensory neurons. The opioids peptides that occur naturally in the human body are endorphins.
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Dr. Jan Lei Iwata
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Last updated Jan 12, 2019

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Neurotransmitter

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