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A 43-year-old member asked:

What neurotransmitters are released by opioid usage?

1 doctor answer3 doctors weighed in
Dr. Paul Grin
Pain Management 37 years experience
Endorphins: Because C-fibers release several excitatory neurotransmitters (e.g., substance P. CGRP), activation of opioid receptors will reduce the release of these transmitters from the presynaptic terminals of afferent sensory neurons. The opioids peptides that occur naturally in the human body are endorphins.

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Last updated Jan 12, 2019

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