A member asked:

What does the des in desloratdine mean?

7 doctors weighed in across 2 answers
Dr. Heidi Fowler answered

Specializes in Psychiatry

It is an: antihistamine. I don't know why the name starts with DES.

Answered 6/21/2015

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Something missing: Des- in chemical use means a molecule that is missing some atoms present in the original molecule. Loratidine is broken down in the body (metabolized) to several break-down products, or metabolites. One of these is desloratidine, which is more active against allergies than the original loratidine. It is missing a side chain with 3 Carbons, 2 Oxygens, and 4 Hydrogens.

Answered 7/6/2017

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