A 38-year-old member asked:
What disease would occur if there is hyposecretion of glucagon?
1 doctor answer • 1 doctor weighed in

Dr. Philip Kernanswered
Endocrinology 45 years experience
Loss of glucagon: People with type 1 diabetes often lose their glucagon after many years. T1DM is a disease of the beta cell in the pancreas, and the alpha cells (which make glucagon) are initially ok. But after many years, diabetics lose the alpha cells too. They can't mobilize glucose from the liver and are prone to hypoglycemia.
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2.1k viewsAnswered >2 years ago
Last updated Nov 1, 2015
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