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A member asked:
In regards to acute intermittent porphyria, what causes abdominal pain?
A doctor has provided 1 answer
Great question: AIP causes an axonal neuropathy which starts in proximal arms but spreads throughout limbs, and likely throughout the body. During the cramping attacks, there is an increase in delta-aminolevulinic acid and porphobiilnogen which likely stimulates abnormal nerve activity within the gut.
Answered 12/12/2017
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