A member asked:

What is the distinction between a severe side effect, and an overdose in regards to the drug amitriptyline? took 9(25mg) for sleep. lost coordination.

9 doctors weighed in across 4 answers
Dr. Oscar Novick answered

Specializes in Pediatrics

Distinction: A severe side effect may be due one tablet or medication taken over a short period. Taking 9 tablets at a time is a deliberate attempt to fo harm

Answered 7/23/2018

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Adverse med effects: Both effects of overdose and adverse effects may be the same,,but the main difference may be that side effects can occur at any dose, while overdose indicates that a dose greater than recommended was taken.

Answered 10/23/2017

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Amitriptyline: Overdose with amitirptyline can lead to ataxia and other coordination problems. Ingestion of 750 mg or greater can lead to serious toxicity. It can also lead heart rhythm problems. If you continue to be symptomatic you need to be seen by a physician

Answered 1/31/2015

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Dr. Georgia Latham answered

Specializes in Family Medicine

Overdose: Nine tablets of amitriptyline (25 mg) would be 225 mg. Almost any person would have sign effects, often intolerable, at that dose. For someone who does not take amitriptyline on a regular basis this dose is high enough to result in symptoms of overdose. This could be very dangerous and even life threatening. Take medications only as prescribed (directed by a physician).

Answered 1/31/2015

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