A member asked:

How accurate is lyme disease western blot?

9 doctors weighed in across 2 answers
Dr. Lori Semel answered

Specializes in Pediatrics

Lyme Disease: Lyme disease is known to inhibit the immune system and twenty to thirty percent of patients have falsely negative antibody tests. Lyme disease has always been a challenge to accurately diagnose in ALL patients with labs. It has to be correlated clinically as there are many false negatives and cases that slip through our fingers.

Answered 1/31/2015

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High disease area?: The Western Blot is the 2nd (after the ELISA) in a 2-step process. An individual in an area where Lyme disease is common & with high exposure to Lyme-disease carrying tick bite who has been bitten by an engorged tick is highly likely to have Lyme disease if these tests are positive. Without these risk factors, a positive test could be falsely positive.

Answered 7/2/2017

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