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A member asked:
Butrans 5mcg/hr, is delivering 0.84mg for the week, the patch claims 5mg per patch, not 0.84mg, is this because 15% dermal bio-availability?
A doctor has provided 1 answer
Transdermal Butrans: Yes. The approximate 15% bioavailability (which is a very complex set of biochem issues) is the main reason. It actually takes about 18 hours for the serum concentations to rise to 25 PICOgrams per mL!!
Answered 9/13/2018
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