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Miami, FL
A 35-year-old female asked:

What are the chances of passing on the cystic fibrosis gene if only one parent is a carrier? other parent not a carrier.

2 doctor answers2 doctors weighed in
Dr. Roy Arnold
Internal Medicine 47 years experience
50-50: One half of offspring will be carriers and one half will not be carriers. No offspring will be afflicted. Thanks for trusting HealthTap!
Dr. James Ferguson
Pediatrics 46 years experience
Flip a coin: Parents give only one gene of every gene pair they have to their offspring. The non-carrier parent will only pass a normal (non-CF) gene since that is all they have. The carrier parent can pass either a CF or a normal gene. Each conception is essentially a flip of a coin (2 outcomes).You could have all non-carrier (normal), all carrier or half normal half carrier offspring.

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Miami, FL
A 35-year-old female asked:

Can a carrier of the Cystic Fibrosis gene ever be symptomatic?

1 doctor answer6 doctors weighed in
Dr. Tanya Russo
Pediatrics 25 years experience
Autosomal recessive: CF is an autosomal recessive genetic disorder. Complete expression of the disease (symptoms) do not typically occur in people who do not have both copies of the defective gene (carriers only have one).

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Last updated Mar 16, 2017
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