I take topirimate and sumatriptan for my migraine is it possible to build a tolerance to them?

Yes: ir is very common to need to go up on the topirimate or switch medications

Not necessarily: However the effectiveness may vary with time. If they are no longer effective discuss with your doctor

Possible: you can build up a tolerance but the real truth is often it is a rebound headache from the medications You need to see your provider and perhaps witch medications or try other methods The rebound headaches are difficult to handle since you think you need more medications and the truth is that the withdrawals are causing the headache