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A 34-year-old female asked:

I read tht tsh rise in pregnancy.i'm hypothyroid n had tsh 4.57 b4 a chemical pregnancy.8 days after 4wk pregnancy miscarriage, its reduced to 0.25. y?

2 doctor answers4 doctors weighed in
Dr. Julie Abbott
Preventive Medicine 47 years experience
Lab error: Hi again, I previously tried to answer your question. Now that I can see that it was the TSH reduced to 0.25, I have to suspect lab error. There would be no reason for your TSH to fall that much during this episode. Either it was mismeasured or misreported, and should be 2.5 mIU/L. Test needs repeating. Best wishes!
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Dr. David Sneid
Endocrinology 43 years experience
Thyroid requirements: can vary significantly during pregnancy and lab must be monitored closely. TSH's are commonly low or low normal in early pregnancy. A TSH of 4.75 is too high if you are attempting conception. Check w/your doctor. Make sure you are on brand name replacement for safety and consistency.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Gerard Honore
Fertility Medicine 31 years experience
Dr. Sneid is 100% correct: TSH drops (gets lower) in the 1st trimester of pregnancy, leading many OBG doctors to wrongly interpret as hyperthyroidism (overactive.) Check with your doctor, this is important.
Nov 13, 2014
Last updated Nov 13, 2014


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