I had a positive hla b27, positive ana, positive sm anitobody, and a positive rnp. and raynauds, is this likely lupus?

Collagen Vascular: The diagnosis of the collagen vascular disease is mainly a clinical diagnosis. The Lab. has confirmatory action on the diagnosis. HLA -B27 positive and relation to some types of auto immune disease including Ankylosing Spondylitis has been proved. But among normal population who never had any evidence of these diseases the HLA-B27 can be found. You might have a non classified auto immune disorder.

Lupus is a clinical: Diagnosis, made based on the presence of physical symptoms and specific organ involvement and is not a diagnosis made by the presence of a genotype or auto antibody. What symptoms have you had that prompted your physician to do this series of tests? What is the opinion of the rheumatologist seeing you (or are you still awaiting a visit with rheum?) These disorders are complex/overlap. Talk w/ URMD