On 45mg of remeron (mirtazapine) for years gained 70 pounds on a diet now wanna cut down on mg of remeron (mirtazapine) will it help to lose weight with my diet ?

If may help but will: still have to work at it. Eat healthfully. Try to eat at least 5 servings of vegetables & 4 of fruit per day. Increase nutritional fiber. Avoid refined sugar & junk carbohydrates. Avoid alcohol, sweetened juices, soda & caffeinated beverages. Aim for 7.5 to 8 hrs of sleep / night. Hydrate w at least 64 oz of water / day. Calories burned must > calories consumed. Do cardio & weight training.