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A member asked:
This is for a psychiatrist. which drug has more of an effect on serotonin,nortriptyline or an ssri like prozac (fluoxetine). please explain, thanks?
8 doctors weighed in across 2 answers
SSRI: SSRI drugs are designed specifically to block the reuptake of serotonin in the appropriate neurons, and thus increase the effect and length of time that serotonin has an effect, several times that is experienced in nature. Nortryptiline is an tri-cyclic antidepressant that has affinity for serotonin receptors, but does not affect the reuptake. Therefore SSRI drugs have greater effect
Answered 5/12/2015
3.6k views
Serotonin drugs: nortriptyline is an tricyclic antidepressant that increases norepinephrine and serotonin but mostly isn't is used for much but sleep now days. Prozac (fluoxetine) works specifically and more efficiently on serotonin.
Answered 2/2/2021
3.6k views
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