Depends...: There are several different types of Pamprin. Pamprin Max formula contains Tylenol, (acetaminophen) Aspirin and caffeine. You wouldn't want to mix this one with Ibuprofen because of the Aspirin. Ibuprofen and Aspirin are too similar. Pamprin Multi-Symptom contains Tylenol, (acetaminophen) Pamabrom (a water pill), and an antihistamine. You could take this one and the Ibuprofen without a problem. Best wishes!
Answered 2/1/2015
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