A member asked:

How does flutamide work to reduce testosterone levels?

A doctor has provided 1 answer
Dr. Alvin Lin answered

Sits on T receptor: Flutamide sits on testosterone receptor but w/o stimulating any testosterone-like function. Because testosterone can't get to receptor, there's no testosterone function. In reality Flutamide doesn't so much reduce testosterone level as much as it reduces testosterone function. Flutamide has since been replaced by Bicalutamide & Nilutamide w/better side effect profiles.

Answered 6/30/2014

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